Or Perish in the Attempt: The Hardship and Medicine of the Lewis and Clark Expedition, by David J. Peck

An ingenious combination of the adventures of Lewis and Clark with an examination of the health problems their expedition faced. A fascinating book that sheds new light not only on Lewis and Clark and the men and one remarkable woman (and her infant) who accompanied them along an eight-thousand-mile path but also the practice of medicine in their time and place.